Description

CJC-1295 No DAC is a synthetic analog of GHRH(1-29) that has been structurally modified at four amino acid positions to improve resistance to enzymatic breakdown while maintaining activity at the GHRH receptor. Because it does not contain the Drug Affinity Complex (DAC) modification, it is associated with a comparatively brief period of activity rather than prolonged hormone exposure. In research settings, this profile is used to study transient pituitary signaling, pulsatile growth hormone release, downstream IGF-1 activity, circadian endocrine patterns, and related metabolic pathways.